Paraguay vs Uruguay prediction, H2H and probable lineups - June 6, 2025
One of the key fixtures of Matchday 15 in the South American World Cup 2026 qualifiers will take place on Friday at the Defensores del Chaco Stadium in Asunción, where Paraguay will host Uruguay. I’m offering a bet on the outcome of this clash with a strong chance of success.
Match preview
After a disastrous start to the qualifiers, Paraguay is experiencing a true renaissance under the guidance of experienced manager Gustavo Alfaro. The team sits fifth with 21 points and has not lost in eight straight matches — one of the most consistent runs in the South American qualifying campaign. The "Guaraníes" have been especially dominant at home: four wins in their last four matches in Asunción.
The squad’s leaders are players who play with heart and passion. Antonio Sanabria, with four goals, is among the top 10 scorers of the qualifiers, while talents like Miguel Almirón and Julio Enciso add variety and pace to the attack. The team is brimming with confidence, and given the opponent’s problems, Paraguay has an excellent chance to extend its successful streak.
Uruguay sits third in the table, but their position is less secure — also on 21 points, but with key absences raising real questions about how the team will cope on this trip. The "Celeste" haven’t tasted victory in their last three matches, and they’re winless in five consecutive away games. Their latest outing ended in a dull 0-0 draw against Bolivia, underlining a clear dip in form.
The absence of key players is particularly painful: Federico Valverde is injured, Rodrigo Bentancur is suspended, and Darwin Núñez is serving a lengthy ban. The loss of such crucial figures disrupts Uruguay’s structure — creativity in midfield drops, and the attack loses its sharpness. Meanwhile, the defense hasn’t been able to compensate for the lack of goals.
Probable lineups
- Paraguay: Fernández, Cáceres, Balbuena (captain), Alderete, Alonso, Galarza, Gómez, Cubas, Almirón, Sanabria, Enciso
- Uruguay: Rochet, Varela, Giménez (captain), Cáceres, Olivera, S. Olivera, Ugarte, Pellistri, Araújo, Viñas, Aguirre
Match facts and head-to-head
- Paraguay are unbeaten in their last 8 matches
- Uruguay are winless in 5 consecutive away games
- The last 4 head-to-head meetings ended with under 2.5 total goals
Prediction
Paraguay’s form and confidence at home are strong arguments in favor of the hosts. Uruguay’s lineup losses are simply too significant, especially in attack, to expect the visitors to play aggressively or produce a high-scoring performance. Given the current scenario, it’s logical to expect Paraguay at least not to lose — and possibly to clinch a narrow victory in a low-scoring affair. Our bet: "Paraguay to win with a (0) handicap" at odds of 1.70.