Bayer vs St. Pauli: prediction, H2H and probable line-ups — February 3, 2026

Bayer Leverkusen vs St. Pauli prediction Stuart Franklin/Getty Images
Finished
3 : 0
Germany, Leverkusen, BayArena
Martin Terrier
32'
Patrik Schick
63'
Jonas Hofmann
90' + 2

This Tuesday, February 3, the BayArena will host a thrilling DFB-Pokal quarter-final showdown as reigning champions Bayer Leverkusen welcome the ambitious St. Pauli. Dive into our in-depth preview and prediction for this high-stakes encounter.

Match preview

The "Pharmacists" continue to showcase their trademark style, built on total control and rapid ball circulation. Fresh off a Champions League victory over Villarreal (2-0) and Bundesliga wins against Werder and Eintracht, Kasper Hjulmand’s squad looks supremely confident. The team hasn’t lost a cup match at home in over two years, and their attacking power—bolstered by the form of Alejandro Grimaldo—poses a threat to any defense.

The hosts’ tactical blueprint remains unchanged: aggressive pressing and exploiting the full width of the pitch. Bayer Leverkusen traditionally rotates their squad in the DFB-Pokal, but their bench depth ensures a consistently high level of play. The main objective for the "Lions" is to avoid underestimating an opponent who has repeatedly proven this season that they can endure and strike on the counter.

St. Pauli, representing the Bundesliga, are a notoriously stubborn side. The "Pirates" are known for their fighting spirit and well-organized defense under Alexander Blessin. Their road to the quarter-finals has been anything but easy, but a recent draw in the Hamburg derby (0-0) and a strong showing against Leipzig (1-1) demonstrate that the visitors are in peak physical condition. For the Hamburg club, the cup is a chance to carve their name into history, and they certainly won’t travel to Leverkusen just to make up the numbers.

The "Brown-and-Whites" will likely rely on a deep defensive block and set-piece opportunities. St. Pauli are experts at "drying out" matches, denying technical opponents space in midfield. The key factor for the visitors will be the performance of goalkeeper Nikola Vasilj, who is expected to be kept busy throughout the full 90 (or possibly 120) minutes.

This promises to be a classic cup battle. Bayer Leverkusen will dominate possession and probe for cracks in the visitors’ defense, while St. Pauli will aim to turn the game into a gritty contest, hoping to pounce on a solitary chance at the other end.

Probable line-ups

Bayer: Blaswich; Quansah, Andrich, Belocian; Vazquez, Maza, Garcia, Grimaldo; Hofmann, Tillman; Schick
St. Pauli: Vasilj; Ando, Wahl, Mets; Pyrka, Sands, Smith, Oppie; Fujita, Kaars, Pereira Lage

Match facts and head-to-head

  • Bayer have won three and drawn two of the last five meetings
  • Bayer are on a three-game winning streak
  • St. Pauli are winless in their last seven matches: four draws and three defeats

Prediction

These encounters are always tense and high-scoring: despite the visitors’ poor form, the cup atmosphere could spark a different mindset. My prediction: total over 2.5 goals at 1.65

Prediction on game Total over 2.5
Odds: 1.65
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