Genoa — Atalanta Prediction, H2H and Probable Lineups — 21 December 2025

Genoa vs Atalanta prediction Photo: https://genoacfc.it/Author unknownn
Serie A Italy (Round 16) 21 dec 2025, 14:45
Finished
0 : 1
Italy, Genoa, Stadio Luigi Ferraris
90' + 4
Isak Hien

On December 21, 2025, in Matchday 16 of Serie A, Genoa will host Atalanta. The match is scheduled to kick off at 20:45 Central European Time. Let’s take a closer look at the potential outcome of this clash.

Genoa

Genoa come into this match in fairly solid form. Despite losing their last home game to Inter 1–2, that defeat was their first in the last six Serie A matches. Prior to that, Genoa recorded three wins and two draws in six league games. However, despite this positive run, their overall situation remains difficult.

Genoa currently sit 16th in the Serie A table with 14 points, just two points above the relegation zone. Their home form has been particularly poor this season. In eight home matches, they have collected only six points, scoring just five goals and conceding eleven. By this metric, Genoa rank 19th in the league.

Recently, Genoa also faced Atalanta in the Coppa Italia Round of 16, where they suffered a heavy 0–4 defeat away in Bergamo. Looking at head-to-head meetings at home against Atalanta, Genoa have struggled significantly. In their last five home matches against this opponent, Genoa have failed to record a single win, losing four times and drawing once. Most of those encounters were high-scoring, with four of the last five matches producing over 2.5 goals and goals scored by both teams.

Atalanta

Atalanta come into this match in very solid form. In their last six matches across all competitions, the team have won five times, suffering only one defeat. That loss came unexpectedly away against Serie A underdogs Verona, where Atalanta were beaten 1–3.

In the Champions League, Atalanta have been particularly impressive, recording two victories in the Champions League against Eintracht Frankfurt and Chelsea. As a result, they are performing confidently in the tournament, currently sitting fifth in the table and maintaining excellent chances of securing direct qualification to the Round of 16.

However, their situation in Serie A is far less convincing. Atalanta currently occupy 12th place in the league standings with 19 points, already 11 points behind the Champions League zone. Their away form in the league has also been inconsistent, as they have collected just six points from seven Serie A away matches. Overall, in their last seven away games across all competitions, Atalanta have recorded two wins, two draws, and three defeats.

After their convincing Coppa Italia victory over Genoa, which was mentioned earlier, Atalanta advanced to the quarter-finals, where they will face Juventus.

Looking at the head-to-head record against Genoa, Atalanta have clearly dominated in recent meetings. They have won each of the last five matches against this opponent, with four of the last matches proving highly productive. In every one of those encounters, Atalanta scored three or more goals against Genoa.

Probable Lineups

  • Genoa: Leali, Marcandalli, Otoa, Vazquez, Norton-Cuffy, Frendrup, Malinovskiy, Ellertsson, Martin, Vitinha, Colombo
  • Atalanta: Carnesecchi, Kolasinac, Ahanor, Scalvini, Bernasconi, Zappacosta, De Roon, Ederson, De Ketelaere, Pasalic, Scamacca

Key Facts and Head-to-Head

  • 8 of Genoa’s last 9 matches have seen over 2.5 goals.
  • In 6 of Genoa’s last 7 matches, both teams scored.
  • Atalanta have won 5 of their last 6 matches.
  • 7 of Atalanta’s last 8 matches have seen over 2.5 goals.
  • In 3 of Atalanta’s last 4 matches, both teams scored.
  • Atalanta have won last 5 head-to-head meetings.
  • Over 2.5 goals have been scored in last 4 head-to-head meetings.
  • In 3 of the last 4 head-to-head meetings, both teams scored.

Genoa — Atalanta Prediction

Both teams come into this match in fairly solid form. Genoa have suffered only one defeat in Serie A over their last six matches. However, the overall situation for the team remains critical. Genoa have already been eliminated from the Coppa Italia and currently sit just two points above the relegation zone in Serie A. Atalanta, on the other hand, are in excellent form. While their league position is still not very high, the team have been performing strongly in the Champions League and showing clear progress in their overall game. In head-to-head meetings, Atalanta hold a significant advantage. They have won five consecutive matches against Genoa, doing so convincingly, with these encounters generally producing a high number of goals. Considering Atalanta’s current form and their motivation to close the gap to the leaders with a break in the Champions League schedule, the team from Bergamo are expected to approach this match with maximum focus. Given the high-scoring trend in recent head-to-head meetings, as well as Genoa’s defensive struggles — as they have conceded in the majority of their recent matches — we expect this game to be open and productive. My bet for this match: Total Over 2 goals at odds of 1.55.

Prediction on game Total over 2
Odds: 1.55
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