The new MLS season kicks off today. Who are the favorites to win in 2025?

The 2025 Major League Soccer season officially begins on February 22 in the United States. Fans can expect another thrilling campaign featuring legends like Lionel Messi, Olivier Giroud, and others aiming for the league title.

This season introduces a new club to MLS, as San Diego FC joins the competition, bringing the total number of teams to 30.

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Bookmakers have already outlined their favorites for the upcoming season. Analysts believe that Inter Miami, led by Lionel Messi, has the highest chances of winning the championship. Other top contenders include LAFC, featuring Hugo Lloris and Olivier Giroud, as well as LA Galaxy, with Marco Reus and Riqui Puig.

Odds to win MLS 2025

🦩 Inter Miami – 4.5
⚫ LAFC – 6.5
⚪ LA Galaxy – 9
🟡 Columbus Crew – 10
🔵 FC Cincinnati – 11
🔴 New York Red Bulls – 15
🟣 Orlando City – 21
🟢 Seattle Sounders – 21
🟠 Houston Dynamo – 21
🔵 Philadelphia Union – 23
🔵 New York City FC – 26
🔴 Real Salt Lake – 26
⚪ Vancouver Whitecaps – 34
🔵 Minnesota United – 34
🔴 Atlanta United – 41
🟠 Colorado Rapids – 41
🟢 Portland Timbers – 41
🔵 Charlotte FC – 41
⚫ D.C. United – 53
🟡 Nashville SC – 53
🟢 Austin FC – 53
🔴 St. Louis City – 53
🟠 Chicago Fire – 53
🔵 CF Montréal – 69
🔴 New England Revolution – 69
⚫ San Diego FC – 69
🔵 San Jose Earthquakes – 69
🟡 Sporting Kansas City – 69
🔵 FC Dallas – 69
🔴 Toronto FC – 69

📅 MLS regular season runs from February 22 to October 18. Defending champions LA Galaxy will aim to retain their title.