Lazio vs Pisa: Preview and analytical prediction for the final Serie A matchday

Lazio vs Pisa prediction Photo by Marco Rosi - SS Lazio/Getty Images
Serie A Italy (Round 38) 23 may 2026, 14:45
Finished
2 : 1
Italy, Rome, Stadio Olimpico, Rome
Fisayo Dele-Bashiru
33'
Pedro Rodriguez
35'
23'
Stefano Moreo

On Saturday, May 23, 2026, the final, 38th round of the Italian Serie A will take place at the Stadio Olimpico in Rome. Lazio will host league outsiders Pisa. The referee team will blow the starting whistle at 20:45 Central European Time.

Team form:

  • Lazio (9th place, 51 points): The Rome-based club is enduring an extremely lackluster and crisis-ridden end to the season under Maurizio Sarri. The team has suffered three consecutive defeats across all competitions with a combined score of 0-7 (including a lost Coppa Italia final to Inter and a 0-2 defeat in the Rome derby against Roma). The "Eagles" can no longer climb above 9th place, but a win is vital to secure a top-10 finish and minimize reputational damage in front of the tifosi.
  • Pisa (20th place, 18 points): The visitors officially confirmed their relegation to Serie B early in May. Under Swedish manager Oskar Hiljemark, the Tuscan side has hit rock bottom, suffering eight straight defeats in the league.

Both teams approach the final matchday with significant squad issues, which will directly impact the attacking potential of this encounter.

  • Lazio squad news: The Romans are facing a severe goalkeeping crisis due to injuries to Ivan Provedel and Edoardo Motta. Inexperienced Alessio Furlanetto will once again start in goal. Moreover, due to suspension, key holding midfielder Nicolò Rovella will not be available, forcing Sarri to field a more static duo of Belahyane and Bašić. Lazio’s negative record (17 matches this season without scoring) highlights the club’s deep systemic creative decline.
  • Pisa squad news: The Tuscans have lost defensive leader Antonio Caracciolo due to yellow card accumulation. Furthermore, Pisa’s attack is the weakest among Europe’s top leagues this spring—just four goals scored since February. Oskar Hiljemark’s side lacks the resources to break down even a depleted Lazio defense.

Head-to-head:

In the reverse fixture in October, Pisa managed to hold Lazio to a goalless draw at home (0-0). The historical trend in Serie A meetings between these teams also points to a distinctly low-scoring pattern: their last five encounters have all ended with under 2.5 total goals.

Probable lineups:

  • Lazio: Furlanetto - Marušić, Gila, Romagnoli, Pellegrini - Belahyane, Bašić, Dele-Bashiru - Isaksen, Noslin, Pedro
  • Pisa: Sěmper - Calabresi, Canestrelli, Bozhinov - Léris, Marin, Aebischer, Akinsamiro, Angori - Stojilković, Moreo

Prediction

Despite a gloomy emotional backdrop after losing the Coppa Italia final and the Rome derby, the huge gulf in squad quality will be decisive in this clash. Lazio are highly motivated to redeem themselves in front of their own tifosi at the Olimpico and end the season on a high note. Even with squad rotation, Maurizio Sarri’s men should fully dominate on the pitch. Therefore, my tip is to back Lazio for the win.

Prediction on game Win Lazio
Odds: 1.58
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4.95
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