Inter vs Pisa prediction, head-to-head and probable lineups - 23 January 2026

Inter vs Pisa prediction Photo: legaseriea.it / Author unknown
Serie A Italy (Round 22) 23 jan 2026, 14:45
Finished
6 : 2
Italy, Milano, Giuseppe Meazza
Piotr Zielinski
39' (P)
Lautaro Martinez
41'
Francesco Pio Esposito
45' + 2
Federico Dimarco
82'
Ange-Yoan Bonny
86'
Henrikh Mkhitaryan
90' + 3
11' 23'
Stefano Moreo

One of the matches of Serie A's 22nd round will take place on Friday at the 'Giuseppe Meazza' stadium in Milan, where league leaders Inter will host relegation-battling Pisa. The hosts remain firmly in the race for the Scudetto and will be looking to assert their favorite status on home turf. I’m backing a bet on goals in this clash, with a strong chance of success.

Match preview

The Nerazzurri head into this fixture following a home defeat to Arsenal in the Champions League, but under Cristian Chivu, Inter have shown remarkable consistency and composure in Serie A. Nine matches unbeaten—including victories over Udinese and Lecce in recent rounds—and an ability to press the advantage in second halves make Inter a dangerous proposition for teams at the lower end of the table.

Squad rotation remains a trusted tool for the coaching staff, and even with key absences, the Milan side maintains balance across all lines. The partnership between Lautaro Martínez and Francesco Esposito is looking increasingly cohesive, while the depth in midfield allows Inter to dictate the tempo right up to the final whistle.

As for Pisa, Alberto Gilardino’s men are still searching for a win after a lengthy drought, but recent performances have shown signs of life, as they've managed to snatch points against the favorites. Draws with Atalanta and Milan, plus a determined display against Napoli, prove that Pisa can trouble even the top clubs.

Their winter signings are starting to settle in, and their commitment to athletic, high-tempo football is particularly evident in away games. Despite their position in the table, Pisa often find opportunities up front and rarely look outclassed, even against league leaders.

Probable lineups

  • Inter: Sommer, Bastoni, Akanji, Bisseck, Augusto, Mkhitaryan, Zieliński, Barella, Henrique, Esposito, Martínez
  • Pisa: Šemper, Calabresi, Caracciolo, Canestrelli, Touré, Marin, Aebischer, Akinsanmiro, Angori, Meiser, Tramoni

Match facts and head-to-head

  • Inter are unbeaten in Serie A for nine games, winning eight of them.
  • Pisa have scored 14 away goals—one of the league’s best tallies, despite not having won on the road.
  • In the reverse fixture, Inter beat Pisa 2-0, with both goals coming in the second half.

Prediction

The gulf in class and squad depth favors the hosts, but Pisa’s fearless away approach could keep things interesting until the final whistle. We believe the visitors will have chances to score, especially with Inter potentially fatigued after European action. The recommended bet here is “Over 2.5 goals” at odds of 1.52.

Prediction on game Total over 2.5
Odds: 1.52
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