Inter vs Genoa: prediction, head-to-head and probable lineups – 28 February 2026
One of the standout fixtures of Serie A's Matchday 27 will take place on Saturday at the Giuseppe Meazza Stadium in Milan, where Inter host Genoa. The home side are returning to domestic action after a painful Champions League exit, while Daniele De Rossi’s Genoa have transformed into one of the most dangerous sides of the season's second half. I’m backing a bet on the total goals in this clash.
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Match preview
Inter suffered a major blow – crashing out against Bodø/Glimt with a 2-5 aggregate was a cold shower for Cristian Chivu’s men. The Norwegians triumphed both at home and in Milan, exposing a lack of energy and flexibility from the Nerazzurri on the European stage. Now, the focus shifts to protecting a ten-point lead in Serie A and fighting on in the Coppa Italia.
Squad news is mixed: Bastoni is suspended, Lautaro Martínez is injured, but Çalhanoğlu and Dumfries are back – though the latter is unlikely to start. Historically, Inter have been ruthless at home against Genoa, boasting 11 straight wins in Milan with a staggering 28:2 aggregate. This is a tradition that truly weighs on the visitors.
Under De Rossi, Genoa are a completely different proposition compared to the autumn version. Last round, the Griffins confidently dispatched Torino (3-0), after dramatic 2-3 results against Lazio and Napoli, and a goalless draw with Cremonese. Just three points separate them from the drop zone, but this team plays bravely, aggressively, and always leaves a mark.
Since De Rossi’s arrival, Genoa have become one of the league’s most prolific sides during this stretch (26 scored, 23 conceded – 49 total goals in their matches). The Genovese are unafraid of favorites: they came back from 0-2 against Bologna (winning 3-2), held Milan (1-1), and often conceded decisive goals only in stoppage time. They head to Milan with nothing to lose – and that’s precisely what makes them dangerous.
Probable lineups
- Inter: Sommer, Bisseck, Acerbi, Akanji, Augusto, Mkhitaryan, Çalhanoğlu, Barella, Darmian, Bonni, Esposito.
- Genoa: Bijlow, Marcandalli, Estigor, Vásquez, Sabelli, Frendrup, Malinovskyi, Ellertsson, Caricol, Oliveira, Colombo.
Match facts and head-to-head
- Inter have not dropped points at home to Genoa in 15 years – 11 consecutive wins in Milan.
- Five of the last six meetings at the Giuseppe Meazza saw over 2.5 total goals.
- Since De Rossi took charge, Genoa’s matches have been among the highest scoring in Serie A (49 total goals).
Prediction
The psychological state around Inter remains the big question – after their European disappointment, regaining confidence quickly is crucial. Genoa will surely create tension and likely find their moment, given their attacking approach in recent months. However, the hosts’ quality, squad depth, and formidable home record tip the balance in favor of the Nerazzurri.
