Betis vs Atletico Madrid: prediction, head-to-head and probable line-ups – 5 February 2026

Real Betis vs Atletico Madrid prediction Photo: laliga.com / Author unknown
Finished
0 : 5
Spain, Seville, Estadio de La Cartuja
12' (OG)
David Hancko
30'
Giuliano Simeone
37'
Ademola Lookman
62'
Antoine Griezmann
83'
Thiago Almada

One of the Spanish Cup quarter-final clashes will take place on Thursday at the Benito Villamarín Stadium in Seville, as local side Betis host Atletico Madrid. This showdown between two of Spain’s most vibrant clubs, each eyeing a coveted semi-final spot, promises a tense and action-packed duel. We offer a betting tip for this match with strong chances of success.

Match preview

Betis approach the match in high spirits and with an improving squad situation. Despite a daunting injury list in January, Manuel Pellegrini’s men managed an impressive run, clinching wins over Feyenoord and Valencia. With Riquelme and Firpo back in the fold, and the possible return of Cucho Hernandez, the hosts’ attacking threat is on the rise.

The Andalusians’ home form this season has been impressive: five consecutive victories since their defeat to Barcelona. However, Pellegrini has historically struggled against Atletico – just one win in 15 head-to-head meetings with Diego Simeone. Still, home support and a refreshed line-up could prove decisive in this cup tie.

Atletico, meanwhile, are experiencing another dip in form – just one win in their last four matches, with two draws and a defeat to Bodo/Glimt. The team has struggled both creatively and in front of goal, and their away performances have been particularly inconsistent. However, facing Betis offers the chance to play on the counter, with more space than they typically find at home. Motivation will be sky-high for Los Colchoneros: the Spanish Cup remains their most realistic shot at silverware this season.

Squad issues persist: Alexander Sorloth is out with a concussion and won’t make the squad. Antoine Griezmann and Giuliano Simeone are back and will spearhead the attack. Pablo Barrios and new signing Ademola Lookman remain doubtful, having missed full training. In case of emergency, Simeone can turn to debutants Rodrigo Mendoza and Obed Vargas, but the focus will be on trusted performers.

Probable line-ups

  • Betis: Adrian, Rodriguez, Nathan, Bartra, Ruibal, Roca, Deossa, Ez Abde, Fornals, Antony, Avila
  • Atletico Madrid: Musso, Llorente, Pubill, Gimenez, Gantzko, Simeone, Cardoso, Koke, Baena, Griezmann, Alvarez

Match facts and head-to-head

  • In four of the last six meetings between Betis and Atletico, only one team found the net.
  • Pellegrini has managed just one win in 15 matches against Simeone.
  • Atletico have won nine of their last 15 away games in Seville.

Prediction

Both teams are far from their peak, but Betis are gradually finding balance, and home support makes them especially dangerous. Atletico, on the other hand, are adept at adapting to their opponents and playing pragmatically on the road. Most likely, the teams won’t be separated in regulation time, with extra time or a penalty shootout set to decide the winner.

Prediction on game Both teams to score - Yes
Odds: 1.68
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